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This dataset contains the expression values of the top 2000 most variable genes for 248 dendritic cell progenitors. Each cell is in one of three maturation stages: MDP, CDP or PreDC. The levels of the factor in sample.info are ordered according to the maturation process.

The number of genes had to be reduced specifically for reducing the package size of SCORPIUS. Use the following code to download the original data:


download.file("https://github.com/rcannood/SCORPIUS/raw/master/data-raw/ginhoux_orig.rds", destfile = "local.rds")
ginhoux <- readRDS("local.rds")
# do something with ginhoux

Usage

ginhoux

Format

A list containing two data frames, expression (248x2000) and sample_info (248x1).

References

Schlitzer A, Sivakamasundari V, Chen J, Sumatoh HR et al. Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow. Nat Immunol 2015 Jul;16(7):718-28. PMID: 26054720

See also